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It's the late 1980s, and Connie Martin, a doctor working for the Epidemiology Intelligence Service of the CDC, is called to Colorado to investigate an alarming outbreak of birth defects. Born illegitimate in the San Luis Valley as Consuela Martín, a name known only to close friends and to her beloved gamer and programmer husband, she arrives as an unknown. Joined by environmental activists who suspect the state's Superfund sites and by doctors and parents who fear for its children, Connie attempts to discover the link between habitat destruction and damage to innocents.