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Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have…mehr

Produktbeschreibung
Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students.

Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations
Autorenporträt
Ram, Jeffrey L.Jeffrey L. Ram is Professor of Physiology at the Wayne State University School of Medicine and the Director of the Belle Isle Aquarium Laboratory in Detroit, MI USA. After receiving a B.A. Magna cum Laude degree in Physics from the University of Pennsylvania (1967) and being a Thouron Scholar at Cambridge University (1967-1968), he earned a Ph.D. degree in Biochemistry and Neurophysiology from the California Institute of Technology (1974). Following post-doctoral research at the University of California Santa Cruz, and a fellowship at the Marine Biological Laboratory in Woods Hole, MA USA, he joined the faculty in the Department of Physiology of Wayne State University in 1977. Ram is known for his studies of the endocrine, neural, and pharmacological control of reproduction, muscle, and digestive physiology in invertebrate model systems, especially Aplysia, his research on invasive mussels, and recent studies on aquatic biodiversity. Together with Dr. Mahadev Murthy (NIH) he developed symposia and publications on the use of model systems for the study of aging, an activity that he has continued as President of the International Society for Invertebrate Reproduction and Development (2014 - 2017). Ram's collaborations on vertebrate systems have included biodiversity studies of the fecal and oral microbiome of animals and people. He has authored or co-authored over 150 publications in these areas and edited the proceedings of several symposia, including a 10 paper issue on model systems for the study of aging for the Journal of Invertebrate Reproduction and Development. The work of his laboratory has been recognized by numerous grants from NIH, NSF, EPA, and various foundations such as the American Heart Association and the Myasthenia Gravis Foundation. Ram is an elected fellow of the American Association for the Advancement of Science. As head of an NSF project to promote the interest of public school students in science and science c

areers, Ram works closely with the Belle Isle Aquarium and the Detroit Public Schools Community District to increase the public understanding of how scientists work and the importance and place of science in protecting the environment.