In a context of globalisation, trade liberalisation and competition, the development of Central African States with fragmented and fragile economies depends largely on their integration; a policy which the leaders logically embraced in 1994 by creating CEMAC which went operational in 1999. However, till date, regional integration in CEMAC is far from being considered as a success story despite member states sharing a common currency. This obliges one to legitimately question the capacity and deployment of the CEMAC Commission; the institution charged with the task to implement regional policies by virtue of Article 25 of the 2009 Revised Treaty of CEMAC. It is against this logic that this book was written. It is a product of in-depth theoretical and practical investigation and has a double dimension; on one hand, it analyses and voices out the constraints faced by the CEMAC Commission, and later suggests measures that can strengthen the Commission with reference to the EU Commission which is arguably a success story. The author has been guided by three main theories; the theory of Development by Integration, the theory of Neo-Functionalism and Comparative Analysis.