Volume 4 of Contemporary Nephrology summarizes major advances in 16 different areas of nephrology during the years 1985 and 1986. Major changes in the composition of the Editorial Board and authorship of the different chapters have occurred in this volume. Six distinguished contributors have retired from the Editorial Board. They include Dr. Zalman A. Agus, Philadelphia; Dr. Robert Anderson, Denver; Dr. Eli Friedman, Brooklyn; Dr. Richard Glassock, Torrance, California; Dr. James Schafer, Birmingham, Alabama; and Dr. Gordon Williams, Bos ton. We are grateful to them for their outstanding…mehr
Volume 4 of Contemporary Nephrology summarizes major advances in 16 different areas of nephrology during the years 1985 and 1986. Major changes in the composition of the Editorial Board and authorship of the different chapters have occurred in this volume. Six distinguished contributors have retired from the Editorial Board. They include Dr. Zalman A. Agus, Philadelphia; Dr. Robert Anderson, Denver; Dr. Eli Friedman, Brooklyn; Dr. Richard Glassock, Torrance, California; Dr. James Schafer, Birmingham, Alabama; and Dr. Gordon Williams, Bos ton. We are grateful to them for their outstanding contributions to the of this series and for their advice and suggestions as first three volumes members of the Editorial Board. They certainly deserve substantial credit for the success of this series. Seven outstanding academicians have joined the Board. They in clude Dr. Vito M. Campese, Professor of Medicine at the University of Southern California, who contributed the chapter on "Recent Advances in the Role of the Renal Nervous System and Renin in Hypertension"; Dr. William G. Couser, Professor of Medicine and Head of the Division of Nephrology at the University of Washington in Seattle ("Immunologic Aspects of Renal Disease"); Dr. Garabed Eknoyan, Professor of Medicine and Vice Chairman of the Department of Medicine at Baylor College of Medicine ("The Uremic Syndrome"); Dr. H. David Humes, Associate Professor of Medicine and Chief of the Nephrology Section at the Uni versity of Michigan Medical School, Veterans Administration Medical Center ("Acute Renal Failure and Toxic Nephropathy"); Dr.
1 Isosmotic Fluid Transport across Epithelia.- 1. Introduction.- 2. Basic Principles.- 3. Isosmotic Water Transport in Epithelia.- References.- 2 Renal Hemodynamics and Sodium Chloride Excretion.- 1. Renal Hemodynamics.- 2. Sodium Chloride Excretion.- 3. Function of Discrete Nephron Segments.- References.- 3 Renal Metabolism.- 1. Introduction.- 2. Cultured Epithelia of Renal Origin: Characteristics and Applications to Physiological and Biochemical Studies.- 3. Role of Liver and Kidney in Acid-Base Homeostasis.- 4. Polyphosphoinositides and Diacylglycerol as Second Messengers.- 5. Renal Ischemia and Anoxia.- References.- 4 Renal Prostaglandins.- 1. Prostaglandin Synthesis Degradation and Excretion by the Kidney.- 2. Interrelationships of Prostaglandins and Vasopressin in the Control of Water Excretion by the Kidney.- 3. Sodium Excretion, Diuretics, and Renal Prostaglandins.- 4. Prostaglandins, Renin Secretion, and Bartter's Syndrome.- 5. Renal Blood Flow, Glomerular Filtration Rate, and Renal Eicosanoids.- 6. Eicosanoids and Renal Disease.- 7. Hypertension, Prostaglandins, and Thromboxane.- 8. Miscellaneous Actions of Renal Eicosanoids.- References.- 5 Acid-Base Physiology and Pathophysiology.- 1. Proximal Tubule.- 2. Metabolic Alkalosis.- 3. Renal Cortical PCO2.- 4. Loop of Henle.- 5. Distal Acidification.- 6. Clinical Studies of Distal Acidification.- 7. Ammonia.- 8. Renal Adaptation to Respiratory Change.- 9. Lactic Acidosis.- References.- 6 Mineral Metabolism.- 1. Vitamin D Endocrine System.- 2. Parathyroid Hormone.- 3. Calcitonin.- 4. Calcium: Physiology and Pathophysiology.- 5. Calicum Nephrolithiasis.- 6. Renal Osteodystrophy.- 7 Recent Advances in the Role of the Renal Nervous System and Renin in Hypertension.- 1. Introduction.- 2. The Renal Sympathetic NervousSystem.- 3. The Renin-Angiotensin System.- References.- 8 Immunologic Aspects of Renal Disease.- 1. Introduction.- 3. Clinical Aspects of Immune Renal Disease.- 4. Diseases That Commonly Present as Nephrotic Syndrome.- 5. Glomerular Involvement in Systemic Immune Diseases.- References.- 9 Acute Renal Failure and Toxic Nephropathy.- 1. Introduction.- 2. Postischemic Acute Renal Failure.- 3. Summary.- References.- 10 The Kidney in Systemic Disease.- 1. Introduction.- 2. Disorders of the Renal Microvasculature.- 3. Renal Consequences of Tumors.- References.- 11 Congenital Renal Disorders and Kidney Tumors: Autosomal Dominant Polycystic Kidney Disease and Renal Cell Carcinoma.- 1. Introduction.- 2. Autosomal Dominant Polycystic Kidney Disease.- 3. Renal Cell Carcinoma.- References.- 12 The Uremic Syndrome.- 1. Introduction.- 2. Uremic Toxins.- 3. Progression of Renal Dysfunction.- 4. The Skin.- 5. The Muscles and Joints.- 6. The Gastrointestinal System.- 7. The Pulmonary System.- 8. The Cardiovascular System.- 9. The Hemopoietic System.- 10. The Immune System.- 11. The Nervous System.- 12. The Endocrine System.- References.- 13 Nutrition in Renal Disease.- 1. Introduction.- 2. Progression of Renal Insufficiency.- 3. Metabolism in CRF.- 4. Nutritional Assessment and Monitoring of Protein Intake.- 5. Trace Elements and Vitamins.- 6. Oxalate.- 7. Nutrition in Childhood Renal Failure.- 8. Nutrition and Renal Transplantation.- 9. Nephrotic Syndrome.- 10. Acute Renal Failure.- References.- 14 Dialysis.- 1. Introduction.- 2. Shortening Treatment Time.- 3. Quantitation of Treatment.- 4. Treatment of Acute Renal Failure.- 5. Peritoneal Dialysis.- 6. Blood-Membrane Interaction and First-Use Syndromes.- 7. Access/Anticoagulation.- 8. Vascular Refilling Rate/Colloid Osmotic Pressure.-9. Reuse.- 10. Hemofiltration.- References.- 15 Renal Transplantation.- 1. Introduction.- 2. Immunogenetics.- 3. Immunosuppression.- 4. Discussion.- References.- 16 Drugs and the Kidney.- 1. Introduction.- 2. The Effects of Renal Disease on Pharmacokinetics and Pharmacodynamics.- 3. Drug Effects on the Kidney.- 4. Clinical Use of Drugs in Renal Failure.- 5. Aspects of Specific Drugs in Patients with Renal Disease or Hypertension.- 6. Nephrotoxicity of Therapeutic Agents.- References.
1 Isosmotic Fluid Transport across Epithelia.- 1. Introduction.- 2. Basic Principles.- 3. Isosmotic Water Transport in Epithelia.- References.- 2 Renal Hemodynamics and Sodium Chloride Excretion.- 1. Renal Hemodynamics.- 2. Sodium Chloride Excretion.- 3. Function of Discrete Nephron Segments.- References.- 3 Renal Metabolism.- 1. Introduction.- 2. Cultured Epithelia of Renal Origin: Characteristics and Applications to Physiological and Biochemical Studies.- 3. Role of Liver and Kidney in Acid-Base Homeostasis.- 4. Polyphosphoinositides and Diacylglycerol as Second Messengers.- 5. Renal Ischemia and Anoxia.- References.- 4 Renal Prostaglandins.- 1. Prostaglandin Synthesis Degradation and Excretion by the Kidney.- 2. Interrelationships of Prostaglandins and Vasopressin in the Control of Water Excretion by the Kidney.- 3. Sodium Excretion, Diuretics, and Renal Prostaglandins.- 4. Prostaglandins, Renin Secretion, and Bartter's Syndrome.- 5. Renal Blood Flow, Glomerular Filtration Rate, and Renal Eicosanoids.- 6. Eicosanoids and Renal Disease.- 7. Hypertension, Prostaglandins, and Thromboxane.- 8. Miscellaneous Actions of Renal Eicosanoids.- References.- 5 Acid-Base Physiology and Pathophysiology.- 1. Proximal Tubule.- 2. Metabolic Alkalosis.- 3. Renal Cortical PCO2.- 4. Loop of Henle.- 5. Distal Acidification.- 6. Clinical Studies of Distal Acidification.- 7. Ammonia.- 8. Renal Adaptation to Respiratory Change.- 9. Lactic Acidosis.- References.- 6 Mineral Metabolism.- 1. Vitamin D Endocrine System.- 2. Parathyroid Hormone.- 3. Calcitonin.- 4. Calcium: Physiology and Pathophysiology.- 5. Calicum Nephrolithiasis.- 6. Renal Osteodystrophy.- 7 Recent Advances in the Role of the Renal Nervous System and Renin in Hypertension.- 1. Introduction.- 2. The Renal Sympathetic NervousSystem.- 3. The Renin-Angiotensin System.- References.- 8 Immunologic Aspects of Renal Disease.- 1. Introduction.- 3. Clinical Aspects of Immune Renal Disease.- 4. Diseases That Commonly Present as Nephrotic Syndrome.- 5. Glomerular Involvement in Systemic Immune Diseases.- References.- 9 Acute Renal Failure and Toxic Nephropathy.- 1. Introduction.- 2. Postischemic Acute Renal Failure.- 3. Summary.- References.- 10 The Kidney in Systemic Disease.- 1. Introduction.- 2. Disorders of the Renal Microvasculature.- 3. Renal Consequences of Tumors.- References.- 11 Congenital Renal Disorders and Kidney Tumors: Autosomal Dominant Polycystic Kidney Disease and Renal Cell Carcinoma.- 1. Introduction.- 2. Autosomal Dominant Polycystic Kidney Disease.- 3. Renal Cell Carcinoma.- References.- 12 The Uremic Syndrome.- 1. Introduction.- 2. Uremic Toxins.- 3. Progression of Renal Dysfunction.- 4. The Skin.- 5. The Muscles and Joints.- 6. The Gastrointestinal System.- 7. The Pulmonary System.- 8. The Cardiovascular System.- 9. The Hemopoietic System.- 10. The Immune System.- 11. The Nervous System.- 12. The Endocrine System.- References.- 13 Nutrition in Renal Disease.- 1. Introduction.- 2. Progression of Renal Insufficiency.- 3. Metabolism in CRF.- 4. Nutritional Assessment and Monitoring of Protein Intake.- 5. Trace Elements and Vitamins.- 6. Oxalate.- 7. Nutrition in Childhood Renal Failure.- 8. Nutrition and Renal Transplantation.- 9. Nephrotic Syndrome.- 10. Acute Renal Failure.- References.- 14 Dialysis.- 1. Introduction.- 2. Shortening Treatment Time.- 3. Quantitation of Treatment.- 4. Treatment of Acute Renal Failure.- 5. Peritoneal Dialysis.- 6. Blood-Membrane Interaction and First-Use Syndromes.- 7. Access/Anticoagulation.- 8. Vascular Refilling Rate/Colloid Osmotic Pressure.-9. Reuse.- 10. Hemofiltration.- References.- 15 Renal Transplantation.- 1. Introduction.- 2. Immunogenetics.- 3. Immunosuppression.- 4. Discussion.- References.- 16 Drugs and the Kidney.- 1. Introduction.- 2. The Effects of Renal Disease on Pharmacokinetics and Pharmacodynamics.- 3. Drug Effects on the Kidney.- 4. Clinical Use of Drugs in Renal Failure.- 5. Aspects of Specific Drugs in Patients with Renal Disease or Hypertension.- 6. Nephrotoxicity of Therapeutic Agents.- References.
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