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The diabetic foot is the leading cause of non-traumatic amputation. The aim of this study was to report on the epidemio-clinical and therapeutic aspects of diabetic foot wounds managed in Antsiranana Madagascar. This retrospective descriptive study included patients with diabetic foot wounds over a 5-year period. Thirty-six cases of diabetic feet were studied. Hospital prevalence was 4% and mean age 57±9 years, with a 55% female predominance. Urban residents were the most represented at 67%. Diabetes was discovered during hospitalization in 55%. In 67% of patients, diabetes had been evolving for less than 5 years. Hypertension was the most common associated risk factor in 39%. The average consultation time was 31±11 days. Wounds occurred spontaneously in 64% of cases. Gangrene was the most common lesion in 45% of cases. Wagner grade 5 was the most common at 33%. Amputation was performed in 36% of patients. Progression was favorable in 67%, and death in 8%.The diabetic foot represents a heavy socio-economic burden. Prevention is the best option.