The research investigates ways of grammatical expression of causal meaning in the structures of the Uzbek and English languages proceeding from the theoretical interpretation given as the method of analysis.Linguistic theory of Moscow linguistic school concerning the form of the word founded by F.F. Fortunatov and developed by his followers M.N. Peterson, A.A. Reformatskiy, M.V. Panov and others is placed on the basis of the method for the description of the languages which are both typologically and genealogically different. This method is used for the analysis of the Uzbek and English languages in the field of the definition of the ways of expressing causal meaning.Analysis of the Uzbek and English literary texts shows that in the structure of compared languages there observed the existence of the grammatical category of causation. The method used for the definition of the grammatical expression of causal meaning excludes the phenomena not meeting the method of systemic description, at the result of which pseudo-causative cases are not included in the system of grammatical expression of causal meaning in this research.