This book is a novel study examining the influence of convergence on cluster-based economic growth in regions. The goal of which is to provide exploratory insights from both national and international perspectives. This study examines the relevant literature in the fields of convergence, clusters, and regions and adopts ideologies from the most salient studies, to create a conceptual framework. There is limited extant literature currently available on the connection between convergence, cluster-based economic growth, and regions. The convergence approach of moving towards equality, bottom-up growth, and co-opetition can be regarded as being imperative to the successful augmentation of a region. Case study examples were taken from an Irish region, a recipient of the European Entrepreneurial Region (EER) award and regions with strong cluster connections. In support of these cases, the first-ever EU Cluster Acceleration Bootcamp programme forms part of this research study which included specific cluster expertise. An exploration of the emergent findings also contributes to both extant practice and the future foundations of cluster research.