The research work carried out for this project is based on the synthesis, structural investigation and its biological aspects. Thiosemicarbazone derivative at 1 or 2 position of the Lawsone ( 2-hydroxy-1,4-naphthalenedione ) is an its important derivative, Which possesses a powerful chelating ability, appreciable analytical utility and significant biological activity. Important conclusions are given as:1) Ni (II) forms complex with these ligands in a squire planar, distorted trigonal prism and capped trigonal prism geometry. 2) It shows the antibacterial and anti fungal activity ISBN: 978-3-8473-2220-7
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