Aim of this work is to analyze the coronavirus viral surface properties related the pattern of electrical features.This chemical physical property is relevant and crucial to set profile of diffusion , severity of disease , efficacy of therapeutic strategy and in order to search new way to fight covid-19 and the NEW VARIANT.The phenomena of immune evasion and the different pattern of efficacy towards variants of some vaccine or some antibodies combination produce the need to verify if considering the electrical feature of viral surface can be a right tool or not.As result of this research it is possible to submit to the scientist that the viral surface properties and electrical feature can be an element to be considered in various preventive or treatment measure.The specificity of action of some vaccine or antibodies seem to tell us that also the aspecific method are useful. Aspecific chemico -physical factors can influence the electrical charges viral surface behavior. hypertonicsaline solution ,humidity, electrical charge barrier in mask are simply example of the effect That can be obtained action on viral surface chemico- physical properties.