On global basis nitrogen is the highly applied and most expensive nutrient used for crop production. Nitrogen fertilization has significantly improved crop productivity since after the invention of synthetic fertilizers but had adversely affected the ecosystem due to its huge application. Therefore, improving crop production and quality without adverse effect on environment and human health are the main challenges for agriculturists. One of the key is to improve nitrogen use efficiency (NUE) of the crops, which will increase the sustainability of agricultural production.