Introduction: SARS-COV-2 infection is a polymorphic disease. Indeed, when it comes to treating those affected by this pandemic, we find that healthcare workers come first.Objectives: To study the epidemiology and characteristics of SARS-COV2 infection among healthcare workers in Gabés. Also, to study the management of protective measures and their use by healthcare workers.Results: Our survey included 100 staff working in the Gabés hospital. The sex ratio was 0.47. The majority of the population (82%) were infected with covid-19, of whom 57 were female and 25 male. Concerning preventive measures, 68% insisted on barrier gestures such as wearing masks, hydroalcoholic gel, regular hand-washing, and distancing staff from each other, or from patients or those accompanying them.Conclusion:The health crisis linked to the Covid19 pandemic has had an impact on healthcare workers in Gabes. Providing the means of prevention, a well-thought-out staffing schedule and psychological support are essential to minimize the adverse consequences of this pandemic.