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Cadmium and lead toxicity is a newly emergence problem particularly in industrial countries, beside pollution of air with industrial fumes, water with sewage contained heavy metals especially cadmium and lead, soil pollution by using of inorganic fertilizers contained those poisonous heavy metals, furthermore contamination of food chain with them increase their danger. Vegetarians are at great risk of cadmium toxicity, beside those whom depend in meat and animal based food. Lead induces changes in C-U bases of influenza virus, and cadmium replaces zinc and copper in sulfhydryl group of it and produces what is known as SARS COV-2. Olfactory dysfunction due to invasion of virus to the olfactory nerve lead to transitional loss or reduction of smell and taste, while taste returns rapidly, smell takes longer time to act properly, this attributed to role of influenza virus in loss of smell which makes dysfunction of this sense more severe than taste. Low hemoglobin lead to absorption of more cadmium which is important for viral replication and lead to severe complications. Women are enriched with cadmium in comparison to men, and that explains why they suffer from serious complications.