Critical Mediators of Multiple Sclerosis Disease Suppression
Na T. N. Gatson
Broschiertes Buch

Critical Mediators of Multiple Sclerosis Disease Suppression

Sex, Pregnancy and Estrogen Responsive Genes

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Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS affecting nearly 3 million people world-wide. Patients present with a myriad of symptoms making MS difficult to diagnose. Clinical presentation of MS ranges from mild to severe, and no two patients can be said to demonstrate the same clinical course. Females are three times as likely as males to be affected, but males often present with a more severe disease course. Pregnancy suppresses MS severity in human and animal models. This is likely due to hormone and genetics regulation of proteins involved with inflammation such as...