Cross Infection Is The Transfer Of Harmful Micro Organism, Bacteria & Virus From One Host (Patient) To Others (Clinician). Cross Infection Is Caused By Unsterilized Medical Equipment, Air Water Spray From Hand Pieces, Bacteria From Coughing & Sneezing (Aerosols), Touching Contaminated Objects. Oral & Maxillofacial Surgeon Comes In Contact With Blood, Saliva, Body Fluids Which Increase The Risk Of Cross Infection From Infected Individual. These Infection Can Cause Serious Complications Like Hepatitis, AIDS, Herpes Simplex (Whitlow) Etc. We Should Work Diligently To Ensure Equipment Safety & Clean Environment. Hence Our Primary Objective Should Be Prevention Of Infections By Pursuance Of Strict Aseptic Protocols For The Patient As Well Operatory Preparation, Frequent & Thorough Hand Washing And Double Gloving In Known Cases Of Blood Borne Infections.