CTLA4 Gene in Type 1 Diabetes
Hatem Saleh
Broschiertes Buch

CTLA4 Gene in Type 1 Diabetes

Genotype & Posttrancription regulation Mechanism

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Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. T cell proliferation is negatively regulated by Cytotoxic Lymphocyte Antigen-4 (CTLA-4). CTLA-4 polymorphisms are associated with T1D in some but not all populations. the author investigated the prevalence of the selected Single Nucleotide Polymorphisms (SNPs) in the entire CTLA-4 gene sequence with the Egyptian population .In this book, the author showed all the basic experimental techniques routinely used in practical Molecular Human Genetics today. No Contemporary...