Gracelyn Portia

CULCASIA FALCIFOLIA

Efficacy and safety in PTZ induced laboratory mice

• Broschiertes Buch

Produktbeschreibung

Epilepsy is a neurological disorder which is characterized with recurrent seizure. The antiepileptic drugs used in the treatment of epilepsy are associated with side effects. Several medicinal plants are used in the traditional treatment of epilepsy due to their therapeutic efficacy with low adverse effects. The leaf of Culcasia falcifolia is a medicinal plant which is traditionally used in Nandi County, Kenya in the treatment of epilepsy. The present study was designed to evaluate the safety, efficacy and antiepiletic activity of ethanol extract of C. falcilofia against PTZ induced seizure in laboratory mice. The study evaluated the anticonvulsant activity of ethanol extracts of Culcasia falcifolia on PTZ induced seizures in mice; the levels of endogenous antioxidant enzyme in brain tissue of the mice; the levels of neurotransmitters in brain tissue of the mice; skeletal muscle relaxation ability and locomotor activity of mice; the phytochemicals present in the extract; and identified and isolated the bioactive phytochemical in the leaf extract.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 80
• Erscheinungstermin: 3. November 2022
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 137g
• ISBN-13: 9786205513583
• ISBN-10: 6205513587
• Artikelnr.: 66383356

Autorenporträt

Soy profesor en el Departamento de Ciencias Biológicas y Agricultura de la Universidad de África Oriental Baraton, Kenia. He supervisado y examinado a estudiantes de posgrado en tesis de investigación. Imparto cursos de biología tanto a nivel de grado como de postgrado. Completé mi doctorado en fisiología animal, mi interés es la investigación de plantas medicinales.