This book is intended to let the public know that nature is the best medicine for all illnesses especially diabetes. It is up to us to discover them. This experimental study was conducted to evaluate the anti-hyperglycemic potency of Asthma Weed (Euphorbia hirta Linn.) leaves crude extract in blood glucose level of female white mice (Mus musculus). It has been found that certain amount of the extract is so potent to lower blood sugar level.