Current and Future Issues in Hemophilia Care

Herausgeber: Rodríguez-Merchán, Emérito Carlos; Valentino, Leonard A

• Gebundenes Buch

Produktbeschreibung

As haemophilia is a life-long condition, continuing supervision by a group of medical personnel is required. In many countries this is provided by comprehensive care haemophilia centres where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons - have specialized knowledge. This new book is a definitive resource on the current aspects and issues around haemophilia. Complications of haemophilia care are well covered in chapters on inhibitors, and musculoskeletal problems, as are all the latest developments in the field of haemophilia.

Produktdetails

• Verlag: John Wiley & Sons / Open Stax Textbooks
• Seitenzahl: 192
• Erscheinungstermin: 18. Juli 2011
• Englisch
• Abmessung: 277mm x 221mm x 15mm
• Gewicht: 794g
• ISBN-13: 9780470670576
• ISBN-10: 0470670576
• Artikelnr.: 33684648

Autorenporträt

E. C. Rodriguez-Merchan, MD, PhD, Consultant Orthopaedic Surgeon, Service of Traumatology and Orthopaedic Surgery, Haemophilia Centre, La Paz University Hospital, Madrid, Spain. Dr Rodriguez-Merchan is a leading orthopaedic surgeon specialising in the treatment of haemophilia. He has 127 articles on PubMed. Leonard A. Valentino, MD, Professor of Pediatrics; Director, Rush Hemophilia and Thrombophilia Center; Past-President, Hemophilia and Thrombosis Research Society, Rush University Medical Center, Chicago, USA. Dr Valentino is a paediatrician specialising in haematology and oncology. He has 60 articles on PubMed.

Inhaltsangabe

List of Contributors. Preface. Part 1: INTRODUCTION. 1 History of
Hemophilia (Caroline Cromwell and Louis Aledort). 2 Hemophilia Care in the
Modern World (Christine A. Lee). 3 Comprehensive Care Model in Hemophilia
(Prasad Mathew). Part 2: GENERAL TOPICS. 4 When Should We Switch From
On-Demand to Prophylaxis Regimen? (José A. Aznar, Andres Moret, Lydia
Abad-Franch, Ana Rosa Cid, Saturnino Haya and Felipe Querol). 5 Prophylaxis
in Children (M. Manco-Johnson). 6 Prophylaxis in Adults with Hemophilia
(Victor Jiménez -Yuste, Emérito-Carlos Rodríguez-Merchán, Maria-Teresa
Alvarez-Román, Monica Martín -Salces). 7 The Economics of Prophylaxis: Does
Prophylaxis with Clotting Factor Represent Value for Money? (Alec Miners).
8 The Transition of Care for the Young Adult Hemophilia Patient (Pia
Petrini). 9 Perinatal Clinical Care and Molecular Diagnosis in Hemophilia
(Carmen Altisent and Francisco Vidal). 10 Managing the Mature Person with
Hemophilia (Savita Rangarajan and Thynn Thynn Yee). 11 Quality of Life in
Hemophilia (Eduardo Remor). Part 3: INHIBITORS. 12 Immunology of Inhibitor
Development (Birgit M Reipert, Christoph J Hofbauer, Katharina N Steinitz,
Hans-Peter Schwarz, FM Horling). 13 Epidemiology of Inhibitors (Johanna G.
Van der Bom) 14 Early Tolerisation to Minimise Inhibitors in PUPS with
Hemophilia A (Günter Auerswald and Karin Kurnik). 15 Prediction of
Inhibitors in Severe Hemophilia (H. Marijke van den Berg and Kathelijn
Fischer). 16 Genetic basis for Inhibitor Development (Johannes Oldenburg
and Anna Pavlova). 17 Non-Genetic Risk Factors for Inhibitor Development
(Lisa N. Boggio and Mindy L. Simpson). Part 4: INHIBITOR TREATMENT. 18
Immune Tolerance Induction Programmes (Jan Blatny and Prasad Mathew). 19
Prophylaxis in Hemophilia A Patients with Inhibitors (Leonard A. Valentino
and Guy Young). 20 Treatment of Bleeding in FVIII Inhibitor Patients (Paul
Giangrande and Jerome Teitel). 21 Discordancy of By-Passing Therapy (Jan
Astermark). Part 5: JOINT HEALTH AND DISEASE. 22 Experimental Studies on
Hemarthrosis, Synovitis and Arthropathy (Leonard A. Valentino and Narine
Hakobyan). 23 Assessment of Joint Involvement in Hemophilia (Erik
Berntorp). 24 Imaging of the Hemophilic Joint (Carmen Martín-Hervásand
Emérito-Carlos Rodríguez-Merchán). 25 Initial and Advanced Stages of
Hemophilic Arthropathy, and Other Musculo-Skeletal Problems: the Role of
Orthopedic Surgery (Emérito-Carlos Rodríguez-Merchán, VictorJiménez -Yuste
and Nicholas J. Goddard). 26 Perioperative Thromboprophylaxis for Persons
with Hemophilia Undergoing Orthopaedic Surgery (Gerry Dolan, Donna M.
Dimichele and Emérito-Carlos Rodríguez-Merchán). Part 6: NEW DEVELOPMENTS.
27 New Technologies for the Pharmacokinetic Improvement of Coagulation
Factor Proteins (Leonard A. Valentino). 28 Current and Future Approaches to
Gene Therapy in Patients with Hemophilia (Maria-Teresa Alvarez- Román,
Monica Martín-Salces, Victor Jiménez -Yuste and Emérito-Carlos
Rodríguez-Merchán). 29 New Developments in Hemophilic Arthropathy
(Emérito-Carlos Rodríguez-Merchán and Leonard A. Valentino). 30
Physiotherapy Evaluation and Intervention in the Acute Hemarthrosis:
Challenging the Paradigm (Nichan Zourikian and Angela L. Forsyth). 31
Laboratory Assays to Predict Response to Bypassing Agents (Benny Sørensen
and Claude Negrier). 32 Combination/Sequential Use of Bypassing Agents
(Alessandro Gringeri). Index.