Doraiswami Ramkrishna is the Harry Creighton Peffer Distinguished Professor of Chemical Engineering at Purdue University, Indiana. He pioneered the development of dynamic metabolic modeling, and has been active in the area for over thirty years. He is a member of the National Academy of Engineering, coined the term 'cybernetic modeling', and has authored several academic books.
1. Introduction
2. Enzymatic adaptation
3. Early development of cybernetic models
4. Revisiting cybernetic laws via optimal control theory
5. Towards modeling of metabolic networks
6. The hybrid cybernetic model (HCM)
7. The lumped hybrid cybernetic model (L-HCM)
8. Predicting dynamic behavior of mutant strains with L-HCM
9. Nonlinear analysis of cybernetic models
10. Metabolic modeling landscape
References
Index.
