Cyclo-oxidation of nitrogen derivatives of lapachol
In search of potentially active derivatives
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If you're looking for methodologies to derivatize natural products, you can find a guide to your goals in this bibliography. Based on reactions of a natural product found in the heartwood of Tabebuia species, popularly known as Ipê, this work sought to synthesize analogues of an alkaloid known as clestofoline, which has excellent medicinal properties already reported in the literature.
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