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Living a healthy life is one's ultimate goal, but the genetics behind the creation of each human is not same. As a curse of human suffering, certain people are born with congenital defects in their menu of the genome. The complexity of cystic fibrosis condition has impacts on several organ systems of the human body perplexing further with secondary infections. It is a complicated disease and scientists across the globe are still trying to comprehend it and formulate a cure because though they narrowed it down to a single target gene, the effects of this disease reach several unfamiliar corners of the human body. Decades of scientific research in the field of chronic diseases like this certainly escalated the level of life expectancy. Scientists and researchers from across the globe have contributed significant information in this all-inclusive book which encompasses three broad sections namely, cystic fibrosis- a system, genetics and biochemistry, and microbiology and immunology.