Plant plays an important role as a source of many anticancer drugs with minimal side effects , for this purpose this study was designed to evaluate the cytotoxic effects of crude and pure extracts of Convolvulus arvensis plant on cancer and transformed cell lines in vitro .This book also included the effect of these extracts on mitotic index on cancer cell line and lymphocytes. The book was demonstrated that the pure extract significantly inhibits the treated cancer cell line proliferation and cause apoptosis. Different methods have been used for detection of apoptosis: light microscope, fluorescent microscope and DNA electrophoresis.