Cytotoxic giant-cell induction & phytoconstituents of Yellow Oleander - Siby, Navya;Jacob, Shija;Thoppil, John E.
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This book entitled "Cytotoxic giant-cell induction & phytoconstituents of Yellow Oleander, Cascabela thevetia (L.) Lippold [Apocynaceae] " reveals the cytotoxicity of C. thevetia, its phytochemical analysis and in situ visualisation of cell death using Evans blue assay. Yellow oleander, a tropical evergreen shrub is a native of West Indies, Southern Mexico and America. The plant possesses phytoconstituents like alkaloids, flavonoids, phenols, terpenoids, saponins, phlobatannins, steroids, tannins, coumarins, proteins and amino acids. A wide spectrum of clastogenic abnormalities like the giant…mehr

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Produktbeschreibung
This book entitled "Cytotoxic giant-cell induction & phytoconstituents of Yellow Oleander, Cascabela thevetia (L.) Lippold [Apocynaceae] " reveals the cytotoxicity of C. thevetia, its phytochemical analysis and in situ visualisation of cell death using Evans blue assay. Yellow oleander, a tropical evergreen shrub is a native of West Indies, Southern Mexico and America. The plant possesses phytoconstituents like alkaloids, flavonoids, phenols, terpenoids, saponins, phlobatannins, steroids, tannins, coumarins, proteins and amino acids. A wide spectrum of clastogenic abnormalities like the giant cells, the strap cells, nuclear budding & lesions, cytoplasmic shrinkage & vacuolation, nuclear & chromosome erosion, apoptotic bodies, nuclear disintegration & extrusion, nuclear diminution, & fragmentation, apoptotic fragmentation of chromatin, nuclear peak formation, pulverization, multiple chromosome bridges, etc. were observed. The non-clastogenic abnormalities scored include micronucleus, bi- & tri-nucleate cells, triple micronuclei, the diagonal arrangement of chromosomes, tripolar anaphase, etc. The study unveils the potential cytotoxic and phytochemical constituents of C. thevetia.
Autorenporträt
The first author Navya Siby is a student and the second author Shija Jacob is a faculty of the Department of Biotechnology & Botany, St.Berchmans College, Changanassery, Kottayam, Kerala, India. The third author Prof. John E. Thoppil is a faculty of the Department of Botany, University of Calicut, Kerala, India.