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High Quality Content by WIKIPEDIA articles! David Chilton Phillips, Baron Phillips of Ellesmere, KBE, FRS (7 March 1924 - 23 February 1999) is considered to be a founding father of the now expanding field of structural biology and was an influential figure in science and government. Among scientists, he will be remembered as the first person ever to determine in atomic detail the structure of the enzyme lysozyme, which he did in the Davy Faraday Research Laboratories of the Royal Institution in London in 1965. Lysozyme, which was discovered in 1922 by Alexander Fleming, is found in tear drops,…mehr

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High Quality Content by WIKIPEDIA articles! David Chilton Phillips, Baron Phillips of Ellesmere, KBE, FRS (7 March 1924 - 23 February 1999) is considered to be a founding father of the now expanding field of structural biology and was an influential figure in science and government. Among scientists, he will be remembered as the first person ever to determine in atomic detail the structure of the enzyme lysozyme, which he did in the Davy Faraday Research Laboratories of the Royal Institution in London in 1965. Lysozyme, which was discovered in 1922 by Alexander Fleming, is found in tear drops, nasal mucus, gastric secretions and egg white. Lysozyme exhibits some antibacterial activity so that the discovery of its structure and mode of action were key scientific objectives. David Phillips solved the structure of lysozyme and also explained the mechanism of its action in destroying certain bacteria by a brilliant application of the technique of X-ray crystallography, a technique towhich he had been introduced as a PhD student at the University in Cardiff, and to which he later made major instrumental contributions.