J.-C. Carel / Paul A. Kelly / Yves Christen (eds.)

Deciphering Growth

Herausgegeben:Carel, J.-C.; Kelly, Paul A.; Christen, Yves

• Gebundenes Buch

Produktbeschreibung

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism's body size, which is not only limited to the size of the brain.

Produktdetails

• Research and Perspectives in Endocrine Interactions
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 11426462, 978-3-540-26192-6
• 2005
• Seitenzahl: 172
• Erscheinungstermin: 8. August 2005
• Englisch
• Abmessung: 241mm x 160mm x 16mm
• Gewicht: 386g
• ISBN-13: 9783540261926
• ISBN-10: 3540261923
• Artikelnr.: 14597825

Autorenporträt

J.-C. Carel, Hopital Saint Vincent de Paul, Paris, France / Paul A. Kelly, INSERM Unit 584, Paris, France / Yves Christen, Fondation Ipsen, Paris, France

Inhaltsangabe

Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Why we are Treating Children with Growth Hormone: Lessons from the French Registry.