The textbook discusses current data on the physical and chemical characteristics, properties and methods of application of materials used in therapeutic and orthopedic dentistry. The manual reflects modern classifications of dental materials, information about their properties, composition, and mechanisms of interaction of components. Each section of the manual contains test tasks. The proposed structure of the manual helps to highlight the main aspects of the materials studied, organize and concretize the educational process.The textbook is developed in accordance with the academic discipline "Materials Science" for students of medical universities studying in the specialty 31.05.03 "Dentistry".