For the industrially developing country like India it is important to use the waste heat from the industries and convert it into useful energy. By using the low grade waste heat sources it is impossible to convert water into its superheated stage. To avail superheated vapour at low temperatures one should go with the refrigerants, which evaporates and condenses at much low temperature than water. The main purpose of this book is to suggest the method for finding the suitable refrigerant for the process, with the parameters of turbine inlet temperature and outlet pressure and pump exit pressure. This book details the design and selection of components for the fabrication of an experimental setup to accomplish the objectives of developing 2.5 kW Organic Rankine Cycle based system.