The book considers ways of implementing digital ecosystems: services, board forms, models. Based on the research the authors have developed a conceptual architecture of ecosystem, which includes semantic core and network infrastructure. The need to implement the semantic core of a new generation of information systems is confirmed by the analysis of modern approaches to the standardization of interaction in the above-mentioned industries. In the monograph simulation modeling of information flows in large networks is presented. The role and importance of information systems design methodology is emphasized, its classification is given.