Economics is a science which studies about wise use of economic resources. Economic resources are labor, land, capital and entrepreneurship. This paper investigates the factors affecting customers' adoption decision of mobile banking in Bako Tibe, Ethiopia. The continuous expansion of technological innovations especially in the banking sector have stirred competition which has changed the way businesses operate resulting in the introduction of mobile banking. This is illustrated that Ethiopia is recently expanding the use of internet banking such as mobile banking. To analysis of the determinants of mobile banking adoption in Bako Tibe, open and semi-structured questionnaires were used. The results of binary logit model indicates that quality of internet, lack of awareness, relative advantage, awareness, trial ability, experience, gender, education, income and age are the factors that are significantly influencing customers' adoption decisions of mobile banking at Commercial Bankof Ethiopia.