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This book attempts to establish the determinants of demand for OPV3 vaccine in Zambia. OPV immunization is one of a combination of vaccines aimed at preventing measles, which is one of the major killers in children in Sub Sahara Africa including Zambia. There are a number of factors that can influence the uptake of immunization vaccines in general and OPV vaccines in particular, hence the desire to understand factors that can significantly improve vaccination uptake.