Pantoprazole sodium were carried out with the help of density bottle, conductivity meter, Stalagmometer and Refractometo meter at various temperatures. It was found that the values of apparent molar volume decrease by increasing temperature from (303 to 318) K. The value of Viscosity increase by increasing the concentration from (0.0025 to 0.01) mol/dm3 at all temperature. The increase in viscosity is due to extent of hydrogen bonding.The Rheochor values also increase by increasing the concentration. The Surface tension values increase by increasing the Concentration from (0.0025 to 0.01) mol/dm3.The Parachor values increase by increasing the Concentration.