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In this research, fatty acids profile, lipid profile, and cardiac biochemical's were studied in myocardial infarction and compared with healthy individuals at Erbil province in Iraq. First about cardiac biochemical's shows the mean S. troponin and CK-MB levels in the normal and MI groups. The results obtained indicate that the mean level of S. troponin and CK-MB in MI group were significantly very higher than that of control group (p0.0001). Then about fatty acid composition provides the Mean ± SD, of each of the total saturated, monounsaturated and poly unsaturated fatty acids in control and MI groups, the results obtained that the mean of S. total saturated fatty acids in MI group was non-significantly higher than that of control group, S. total monounsaturated fatty acids in MI significantly (P0.05) lower than that of control group, and S. total polyunsaturated fatty acids in MI group significantly (P0.001) lower than that of control group. Finally, the Mean ± SD, of each of the lipid profile, indicated that each of S. triglycerides and S. total cholesterol in MI were significantly higher than that of controls (P0.001), S.LDL in MI group was significant.