Development of a CellChip based Multi-Well-Type Bioreactor - Zimmer, Gerald
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In this work a novel multi-purpose platform for the three-dimensional cultivation of cells is described, its main component being a polymer chip (CellChip) that features a microstructured area of 1-2cm2. The microstructured area is realized as a grid of micro-containers measuring 300µm in depth, length and height. Depending on the cells and the chip type used up to 7 106 cells can be cultivated on one chip. For the facilitation of nutrient and oxygen supply the CellChip can be inserted into a bioreactor housing that can be tailored to the specific application. For drug screening and other…mehr

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Produktbeschreibung
In this work a novel multi-purpose platform for the
three-dimensional cultivation of cells is described,
its main component being a polymer chip (CellChip)
that features a microstructured area of 1-2cm2.
The microstructured area is realized as a grid of
micro-containers measuring 300µm in depth, length
and height. Depending on the cells and the chip type
used up to 7 106 cells can be cultivated on one chip.
For the facilitation of nutrient and oxygen supply
the CellChip can be inserted into a bioreactor
housing that can be tailored to the specific
application. For drug screening and other high-
throughput purposes a bioreactor with microtiter
plate-footprint was developed in this work. Up to 12
CellChips can be incorporated into this bioreactor
with independent nutrient and oxygen supply.
Autorenporträt
Gerald Zimmer, gebohren am 18.06.1975 in Güssing, Österreich, begann 2002 das
Studium der Biotechnologie, Sponsion 2006, seit 2007 Studium der
medizinischen Wissenschaften. Verheiratet seit 2007, noch keine
Kinder.