Despite the scientific breakthroughs recorded in the management of diabetes mellitus over the last decade, stemming the increasing incidence of diabetes mellitus and providing a long-term effective management of the disease and its complications remain elusive to scientists and medical experts in the field of diabetology. This book provides an up-to-date insight into diabetes mellitus as a disease entity, examines the aetiopathological basis and the course of the disease, its cellular and molecular mechanisms as well as its diagnosis and monitoring. While providing an insight into the experimental techniques employed in the study of diabetes and their outcomes, the book, also provides an overview of the current conventional management modalities, as well as, the exciting results of some selected African, Asian and American single and multiherbal remedies that are popularly used in the disease management. Evidence-based results and prospects emanating from both preclinical and clinical studies of the antihyperglycaemic effects of these herbs indicate that these could soon become the ultimate alternatives to the disease management.