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Hepatocellular carcinoma is a primary liver cancer. It is the most common cause of death in patients suffering from cirrhosis. Most individuals with hepatocellular carcinoma exhibit signs and symptoms consistent with chronic liver disease. Other risk factors that can contribute to an incidence of this condition include chronic hepatitis B and C, Type 2 diabetes, nonalcoholic steatohepatitis, Wilson's disease, etc. The carcinoma can be detected through blood testing and imaging evaluation, especially MRI. The treatment of hepatocellular carcinoma and its prognosis depends on factors such as tumor size, spread, histology and patient health. Surgical resection, liver transplantation, arterial catheter-based treatment and systemic therapy are certain therapies for the management of hepatocellular carcinoma. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of hepatocellular carcinoma. The objective of this book is to give a general view of the diagnosis and treatment of hepatocellular carcinoma. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this area of study.