Necrotizing enterocolitis (NEC) in neonates is the most common cause of postnatal critical illness of inflammatory genesis. For a long time, pathological conditions such as functional intestinal obstruction, intra-abdominal abscess, spontaneous ileum perforation, appendicitis, necrotizing colitis in neonates with perforation, ischaemic enterocolitis and infarction of the neonatal bowel were synonymous with NEC. Thus, until almost the second half of the last century. Necrotising enterocolitis is a severe disease of the neonatal period, which is an inflammation of the intestinal wall followed by its necrosis. The incidence is 2.4 per 1000 newborns. The incidence of NEC ranges from 1 to 8% amongst children in intensive care units. Grade I-III prematurity is found in 63% of cases. Treatment has been difficult to date. Mortality remains high. Development of recommendations for the diagnosis of treatment and rules for the care of the newborn.