Andere Kunden interessierten sich auch für
![Hirschsprung's disease in the pediatric surgery department]( "Hirschsprung's disease in the pediatric surgery department")
Hirschsprung's disease in the pediatric surgery department42,99 €![Different Roles of Immunohistochemical Markers in Cancer]( "Different Roles of Immunohistochemical Markers in Cancer")
Different Roles of Immunohistochemical Markers in Cancer25,99 €![Late post Operative Complication of Hirschsprung's disease]( "Late post Operative Complication of Hirschsprung's disease")
Late post Operative Complication of Hirschsprung's disease38,99 €![Management of vasoocclusive crises in sickle cell disease patients]( "Management of vasoocclusive crises in sickle cell disease patients")
Management of vasoocclusive crises in sickle cell disease patients30,99 €![Diagnosis and assessment of tuberculosis]( "Diagnosis and assessment of tuberculosis")
Diagnosis and assessment of tuberculosis30,99 €![LYMPHOMA OF THE LYMPH NODE MARGINAL ZONE]( "LYMPHOMA OF THE LYMPH NODE MARGINAL ZONE")
LYMPHOMA OF THE LYMPH NODE MARGINAL ZONE41,99 €![¿ype II Osteoporosis Pathogenesis as a Result of Secondary Edentulous]( "¿ype II Osteoporosis Pathogenesis as a Result of Secondary Edentulous")
¿ype II Osteoporosis Pathogenesis as a Result of Secondary Edentulous17,99 €
Hirschsprung's disease (HD) is a rare congenital disorder defined by the absence of ganglion cells (GCs) in a segment of the digestive tract. Its diagnosis in Tunisia relies solely on histopathological study with hemathein-eosin. Currently, several studies are being carried out on biomarkers of MH, notably on the anti-calretinin antibody. The aim of our work was to evaluate the diagnostic performance of the anti-calretinin antibody in the context of suspected HD. This was a retrospective study including 69 patients with MH. An immunohistochemical study with anti-calretinin antibody was performed. In MPA biopsies, CGs were labeled in 2 biopsies, while interstitial nerve fibers were labeled in 3 biopsies. The sensitivity, specificity, positive predictive value and negative predictive value of the anti-calretinin antibody were 93%, 100%, 100% and 70% respectively.The use of an immunohistochemical study with anti-calretinin antibody in the absence of GC is a reasonable alternative inview of the serious therapeutic implications of HD.