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The book is devoted to the topical problem of maladaptation. It reflects the main factors that lead to this phenomenon. Age-related changes in the severity of indicators of school desadaptation are accompanied by desadaptation changes at both socio-psychological and psychophysiological levels of psychological adaptation to school in children 7-9 years old. The optimal values of functioning of psychophysiological mechanisms of regulation of pupils heart, providing the process of adaptation of pupils of school age to school learning are established.Practical solutions to the problems of school disadaptation are found in the scientific and methodological developments aimed at an early diagnosis of its symptoms and risk factors, the creation of differentiated correctional programs that include methods of psychological correction of violations of personal development in these children and the search for effective psychological and pedagogical support for teachers and parents of disadapted students.