Walterhouse

Diagnostic and Therapeutic Advances in Pediatric Oncology

Herausgeber: Walterhouse, David O., Cohn, Susan L.

• Gebundenes Buch

Produktbeschreibung

The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in the book describe models for understanding the causes of childhood cancer which were perhaps initially identified by clinicians and which are now being studied and understood by researchers. These chapters describe research evidence supporting roles for involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the application of new research developments to clinical practice in the most common forms of solid tumors of childhood outside the central nervous system. The final chapter describes late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects. The emphasis on bridging research developments with clinical practice makes this book a unique resource for researchers and clinicians as the application of research developments to clinical practice increases and as clinical observations are studied with modern res earch tools.

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Produktdetails

• Cancer Treatment and Research 92
• Verlag: Springer Netherlands
• 1998
• Seitenzahl: 404
• Erscheinungstermin: 31. Januar 1998
• Englisch
• Abmessung: 241mm x 160mm x 28mm
• Gewicht: 839g
• ISBN-13: 9780792399780
• ISBN-10: 0792399781
• Artikelnr.: 23404570

Inhaltsangabe

Section I: Understanding the Causes of Tumors of Childhood. 1. Embryonic Development and Pediatric Oncogenesis; D.O. Walterhouse, Joon Won Yoon. 2. Immunodeficiency States and Related Malignancies; K.L. McClain. 3. Familial Cancer Syndromes and Genetic Counseling; G. Tomlinson. Section II: Embryonal Tumors. 4. Molecular Basis of Wilms' Tumor; P. Grundy. 5. Neuroblastoma: Solving a Biologic Puzzle; S.L. Cohn, et al. 6. Pediatric Germ Cell Tumors; E.J. Perlman, C. Kretschmar. 7. Hepatic Malignancies in Childhood and Adolescence; E.C. Douglass. Section III: Sarcomas. 8. Osteosarcoma; J.S. Dome, C.L. Schwartz. 9. The Ewing Sarcoma Family of Tumors: Ewing Sarcoma and Peripheral Primitive Neuroectodermal Tumor of Bone and Soft Tissue; L. Granowetter, D.C. West. 10. Rhabdomyosarcoma: Biology and Therapy; A.S. Pappo, D.N. Shapiro. Section IV: Late Effects of Childhood Cancer. 11. Late Effects of Cancer Therapy; E.R. Morgan, M. Haugen. Index.