Andere Kunden interessierten sich auch für
![Nigella sativa Linn. ameliorates D-galactosamine/LPS induced hepatitis]( "Nigella sativa Linn. ameliorates D-galactosamine/LPS induced hepatitis")
Nigella sativa Linn. ameliorates D-galactosamine/LPS induced hepatitis36,99 €![Le trisulfure de diallyle améliore la néphrotoxicité induite par l'arsenic chez le rat]( "Le trisulfure de diallyle améliore la néphrotoxicité induite par l'arsenic chez le rat")
Le trisulfure de diallyle améliore la néphrotoxicité induite par l'arsenic chez le rat23,99 €![Health benefit Of Diallyl Disulphide in Pollutant caused Renal Disease]( "Health benefit Of Diallyl Disulphide in Pollutant caused Renal Disease")
Health benefit Of Diallyl Disulphide in Pollutant caused Renal Disease40,99 €![Anti-Oxidative Properties of Bamboo Leaves]( "Anti-Oxidative Properties of Bamboo Leaves")
Anti-Oxidative Properties of Bamboo Leaves23,99 €![Study of the western style diet risk factors on kidney]( "Study of the western style diet risk factors on kidney")
Study of the western style diet risk factors on kidney23,99 €![Nanofiltration in the Mitigation of Arsenic Pollution in Water]( "Nanofiltration in the Mitigation of Arsenic Pollution in Water")
Nanofiltration in the Mitigation of Arsenic Pollution in Water32,99 €![History of kidney diseases and stem cells]( "History of kidney diseases and stem cells")
History of kidney diseases and stem cells26,99 €
Abstract In this study, we aim to investigate the protective role of Diallyl trisulfide (DATS) on preventing the Arsenic (As) induced oxidative stress mediated renal injury in rats. DATS pre-administration to As intoxicated rats shows towards normalization on the levels of urea, uric acid, creatinine, creatinine clearance, urobilinogen, specific gravity and RBCs and WBCs count. As exposure elevated the renal oxidative stress markers, TNF- , IL-6 and IL- beta, Keap-1and GSK3 beta protein, Bax and Cytosolic cytochrome C, NADPH oxidases, iNOS and NF B expressions. As also decreased the levels of renal enzymatic and non enzymatic antioxidants, renal membrane bound ATPases and the expression levels of Nrf2, HO-1, Gamma-GCS, SOD1, SOD2, p-Akt, Akt, PI3K and Bcl-2. DATS pre-administration has proved an effective recovery by attenuating the alterations induced by As in the renal tissue which has been further supported by the histological and ultrastructural observations. These results suggest that DATS may be a prospective nephroprotective entity as an antioxidant against As induced renal oxidative dysfunction.