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The global impact of Diabetes Mellitus and its effect on oral health is alarming. The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014. Diabetes Mellitus and Chronic Periodontitis share a bi-directional relationship. Improvement in the glycaemic index of diabetic patients leads to an improvement in periodontal status and vice-versa. The present clinical and microbiological study was conducted with an aim to improve the periodontal status in medically compromised type 2 diabetes mellitus with chronic periodontitis. Limited research in this field demanded the need for further clinical research on diabetes mellitus and oral health. As we all know poor glycemic control further worsens the periodontal status which further increases the morbidity. Therefore, the need of the present clinical research was to assess whether soft tissue diode laser therapy, when used as an adjunct to non-surgical periodontal therapy, leads to a better improvement in glycemic index(HbA1c) in type 2 Diabetes Mellitus patients affected with Chronic Periodontitis.