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Dioxin (2,3,7,8 TCDD) is a Persistent Organic Pollutant. Which is unintentionally produced by various sources like chemical bleaching process, Municipal Incineration, etc. TCDD is a most potent congener which enters into different systems of animal and human beings causing various toxicological effects. Almost all organs are affected by TCDD, following oxidative stress in the animal system and effects on physiological and biochemical activities. TCDD can not be degraded easily by any chemical or biological processes.