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This book provides detailed summary about Dipeptidyl Peptidase IV (DPP IV) Inhibitors in Management of Type 2 Diabetes. DPP IV inhibitors are established therapy for managing blood glucose in patients with type 2 diabetes. Several DPP IV inhibitors are developed in last few years and are used clinically all over the world. This book describes role of Glucagon Like Peptide-1 (GLP-1), an incretin hormone in insulin secretion and how DPP IV inhibitors affect action of GLP-1. It is followed by chemistry of DPP IV inhibitors and their lead optimization strategies for clinical development.

Produktbeschreibung
This book provides detailed summary about Dipeptidyl Peptidase IV (DPP IV) Inhibitors in Management of Type 2 Diabetes. DPP IV inhibitors are established therapy for managing blood glucose in patients with type 2 diabetes. Several DPP IV inhibitors are developed in last few years and are used clinically all over the world. This book describes role of Glucagon Like Peptide-1 (GLP-1), an incretin hormone in insulin secretion and how DPP IV inhibitors affect action of GLP-1. It is followed by chemistry of DPP IV inhibitors and their lead optimization strategies for clinical development.
Autorenporträt
Dr. Jagatkumar Upadhyay have more than 10 years of academic experience and 3 years of research experience in Drug Discovery Research. His research areas include  computer-aided drug design techniques, synthesis of heterocyclic compounds and green chemistry.