Discovery of Small-Molecule Modulators of Protein-RNA Interactions for Treating Cancer and COVID-19
Wan Gi Byun
Gebundenes Buch

Discovery of Small-Molecule Modulators of Protein-RNA Interactions for Treating Cancer and COVID-19

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This book describes the development of novel protein-RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein-RNA interactions to treat cancer and COVID-19.Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening...