Disseminated intravascular coagulation (DIC) corresponds to excessive systemic activation of the coagulation process. An underlying etiology must always be sought. In the case of an infectious cause, rapid identification of the causative agent, and consequent initiation of appropriate treatment, can improve the patient's prognosis. In fact, although symptomatic treatment of DIC is essential to control its clinical impact, the cornerstone of treatment remains the management of the underlying etiology, particularly in the case of infection, given the relative ease of initiating treatment compared with neoplastic pathologies.The aim of our work was to study the clinical and biological characteristics of DIC of infectious origin, to identify the infectious agents and to define its evolution.