Drug Design
Structure- And Ligand-Based Approaches
Herausgeber: Merz Jr, Kenneth M; Reynolds, Charles H; Ringe, Dagmar
Schade – dieser Artikel ist leider ausverkauft. Sobald wir wissen, ob und wann der Artikel wieder verfügbar ist, informieren wir Sie an dieser Stelle.
Drug Design
Structure- And Ligand-Based Approaches
Herausgeber: Merz Jr, Kenneth M; Reynolds, Charles H; Ringe, Dagmar
- Gebundenes Buch
- Merkliste
- Auf die Merkliste
- Bewerten Bewerten
- Teilen
- Produkt teilen
- Produkterinnerung
- Produkterinnerung
This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200 images.
Andere Kunden interessierten sich auch für
- Antisense Therapeutics110,99 €
- Mechanobiology of Cell-Cell and Cell-Matrix Interactions110,99 €
- Liposomes110,99 €
- Lars F. WestbladeLarone's Medically Important Fungi132,99 €
- Wilhelm RouxDer Kampf der Teile im Organismus59,00 €
This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200 images.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 286
- Erscheinungstermin: 31. Mai 2010
- Englisch
- Abmessung: 287mm x 225mm x 22mm
- Gewicht: 1187g
- ISBN-13: 9780521887236
- ISBN-10: 0521887232
- Artikelnr.: 27871361
- Verlag: Cambridge University Press
- Seitenzahl: 286
- Erscheinungstermin: 31. Mai 2010
- Englisch
- Abmessung: 287mm x 225mm x 22mm
- Gewicht: 1187g
- ISBN-13: 9780521887236
- ISBN-10: 0521887232
- Artikelnr.: 27871361
Preface; 1. Progress and issues for computationally guided lead discovery
and optimization William L. Jorgensen; Part I. Structural biology: 2. X-ray
crystallography in the service of structure-based drug design Gregory A.
Petsko and Dagmar Ringe; 3. Fragment-based structure-guided drug discovery:
strategy, process, and lessons from human protein kinases Stephen K.
Burley, Gavin Hirst, Paul Sprengeler and Siegfried Reich; 4. NMR in
fragment-based drug discovery Christopher A. Lepre, Peter J. Connolly and
Jonathan M. Moore; Part II. Computational Chemistry Methodology: 5.
Free-energy calculations in structure-based drug design Michael R. Shirts,
David L. Mobley and Scott P. Brown; 6. Studies of drug resistance and the
dynamic behavior of HIV-1 protease through molecular dynamics simulations
Fangyu Ding and Carlos Simmerling; 7. Docking: a domesday report Martha S.
Head; 8. The role of quantum mechanics in structure-based drug design
Kenneth M. Merz; 9. Pharmacophore methods Steven L. Dixon; 10. QSAR in drug
discovery Alexander Tropsha; 11. Predicting ADME properties in drug
discovery William J. Egan; Part III. Applications to drug discovery: 12.
Computer-aided drug design: a practical guide to protein-structure-based
modeling Charles H. Reynolds; 13. Structure-based drug design case study:
p38 Arthur M. Doweyko; 14. Structure-based design of novel P2-P4
macrocyclic inhibitors of hepatitis C NS3/4A protease M. Katharine Holloway
and Nigel J. Liverton; 15. Purine nucleoside phosphorylases as targets for
transition-state analog design Andrew S. Murkin and Vern L. Schramm; 16.
GPCR 3D modeling Frank U. Axe; 17. Structure-based design of potent
glycogen phosphorylase inhibitors Qiaolin Deng.
and optimization William L. Jorgensen; Part I. Structural biology: 2. X-ray
crystallography in the service of structure-based drug design Gregory A.
Petsko and Dagmar Ringe; 3. Fragment-based structure-guided drug discovery:
strategy, process, and lessons from human protein kinases Stephen K.
Burley, Gavin Hirst, Paul Sprengeler and Siegfried Reich; 4. NMR in
fragment-based drug discovery Christopher A. Lepre, Peter J. Connolly and
Jonathan M. Moore; Part II. Computational Chemistry Methodology: 5.
Free-energy calculations in structure-based drug design Michael R. Shirts,
David L. Mobley and Scott P. Brown; 6. Studies of drug resistance and the
dynamic behavior of HIV-1 protease through molecular dynamics simulations
Fangyu Ding and Carlos Simmerling; 7. Docking: a domesday report Martha S.
Head; 8. The role of quantum mechanics in structure-based drug design
Kenneth M. Merz; 9. Pharmacophore methods Steven L. Dixon; 10. QSAR in drug
discovery Alexander Tropsha; 11. Predicting ADME properties in drug
discovery William J. Egan; Part III. Applications to drug discovery: 12.
Computer-aided drug design: a practical guide to protein-structure-based
modeling Charles H. Reynolds; 13. Structure-based drug design case study:
p38 Arthur M. Doweyko; 14. Structure-based design of novel P2-P4
macrocyclic inhibitors of hepatitis C NS3/4A protease M. Katharine Holloway
and Nigel J. Liverton; 15. Purine nucleoside phosphorylases as targets for
transition-state analog design Andrew S. Murkin and Vern L. Schramm; 16.
GPCR 3D modeling Frank U. Axe; 17. Structure-based design of potent
glycogen phosphorylase inhibitors Qiaolin Deng.
Preface; 1. Progress and issues for computationally guided lead discovery
and optimization William L. Jorgensen; Part I. Structural biology: 2. X-ray
crystallography in the service of structure-based drug design Gregory A.
Petsko and Dagmar Ringe; 3. Fragment-based structure-guided drug discovery:
strategy, process, and lessons from human protein kinases Stephen K.
Burley, Gavin Hirst, Paul Sprengeler and Siegfried Reich; 4. NMR in
fragment-based drug discovery Christopher A. Lepre, Peter J. Connolly and
Jonathan M. Moore; Part II. Computational Chemistry Methodology: 5.
Free-energy calculations in structure-based drug design Michael R. Shirts,
David L. Mobley and Scott P. Brown; 6. Studies of drug resistance and the
dynamic behavior of HIV-1 protease through molecular dynamics simulations
Fangyu Ding and Carlos Simmerling; 7. Docking: a domesday report Martha S.
Head; 8. The role of quantum mechanics in structure-based drug design
Kenneth M. Merz; 9. Pharmacophore methods Steven L. Dixon; 10. QSAR in drug
discovery Alexander Tropsha; 11. Predicting ADME properties in drug
discovery William J. Egan; Part III. Applications to drug discovery: 12.
Computer-aided drug design: a practical guide to protein-structure-based
modeling Charles H. Reynolds; 13. Structure-based drug design case study:
p38 Arthur M. Doweyko; 14. Structure-based design of novel P2-P4
macrocyclic inhibitors of hepatitis C NS3/4A protease M. Katharine Holloway
and Nigel J. Liverton; 15. Purine nucleoside phosphorylases as targets for
transition-state analog design Andrew S. Murkin and Vern L. Schramm; 16.
GPCR 3D modeling Frank U. Axe; 17. Structure-based design of potent
glycogen phosphorylase inhibitors Qiaolin Deng.
and optimization William L. Jorgensen; Part I. Structural biology: 2. X-ray
crystallography in the service of structure-based drug design Gregory A.
Petsko and Dagmar Ringe; 3. Fragment-based structure-guided drug discovery:
strategy, process, and lessons from human protein kinases Stephen K.
Burley, Gavin Hirst, Paul Sprengeler and Siegfried Reich; 4. NMR in
fragment-based drug discovery Christopher A. Lepre, Peter J. Connolly and
Jonathan M. Moore; Part II. Computational Chemistry Methodology: 5.
Free-energy calculations in structure-based drug design Michael R. Shirts,
David L. Mobley and Scott P. Brown; 6. Studies of drug resistance and the
dynamic behavior of HIV-1 protease through molecular dynamics simulations
Fangyu Ding and Carlos Simmerling; 7. Docking: a domesday report Martha S.
Head; 8. The role of quantum mechanics in structure-based drug design
Kenneth M. Merz; 9. Pharmacophore methods Steven L. Dixon; 10. QSAR in drug
discovery Alexander Tropsha; 11. Predicting ADME properties in drug
discovery William J. Egan; Part III. Applications to drug discovery: 12.
Computer-aided drug design: a practical guide to protein-structure-based
modeling Charles H. Reynolds; 13. Structure-based drug design case study:
p38 Arthur M. Doweyko; 14. Structure-based design of novel P2-P4
macrocyclic inhibitors of hepatitis C NS3/4A protease M. Katharine Holloway
and Nigel J. Liverton; 15. Purine nucleoside phosphorylases as targets for
transition-state analog design Andrew S. Murkin and Vern L. Schramm; 16.
GPCR 3D modeling Frank U. Axe; 17. Structure-based design of potent
glycogen phosphorylase inhibitors Qiaolin Deng.