James H. Goldie, Andrew J. Coldman, J. H. Goldie

Drug Resistance in Cancer

• Broschiertes Buch

Produktbeschreibung

An accessible and sophisticated account of the biological mechanisms of drug resistance in cancer and their mathematical modelling.

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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 256
• Erscheinungstermin: 31. Januar 2009
• Englisch
• Abmessung: 229mm x 152mm x 15mm
• Gewicht: 421g
• ISBN-13: 9780521111706
• ISBN-10: 0521111706
• Artikelnr.: 26034112

Inhaltsangabe

Preface
1. The biological basis of cancer and the problem of drug resistance
2. Tumour growth, stem cells and experimental chemotherapy
3. Molecular aspects of drug resistance
4. Quantitative descriptions of the origins of drug resistance
5. Development and exploration of the random mutation model for drug resistance
6. Extensions of the random mutation model for drug resistance
7. Clinical predictions of the random mutation model
8. Directed versus random mutation and the problem of intrinsic resistance
9. Some final thoughts on the problem of drug resistance
Index.