List of contributors
Series editor's preface
Abbreviations
1. Resistance mechanisms to antimetabolites Erdem Göker, Richard Gorlick and Joseph R. Bertino
2. Resistance to antitumor alkylating agents and cisplatin Beverly A. Teicher and Emil Frei III
3. The MDR genes Lyn Mickley and Antonio Tito Fojo
4. Topoisomerase genes and resistance to topoisomerase inhibitors Giuseppe Giaccone
5. Genes that modulate apoptosis: major determinants of drug resistance John A. Hickman
6. Clinical implications of drug resistance Henk M. W. Verheul and Herbert M. Pinedo
7. The reversal of multidrug resistance William S. Dalton
8. Effect of dose and schedule on chemotherapeutic drug resistance David Fennelly, George Raptis, John P. A. Crown and Larry Norton
9. Circumvention of drug resistance by high-dose chemotherapy in solid tumors Elisabeth G. E. de Vries, Wil Dolsma, Geke A. P. Hospers and Nanno H. Mulder
10. Enhancing drug effectiveness by gene transfer Karol Sikora
Index.
