Over the years, adolescent girls have always found it difficult to overcome the stress of life that their immediate societies have inflicted on them.Due to excruciating poverty and structural inequality within various families and the impacts of this awkward situation on most adolescent girls, the delivery of the quality of social support services and cares to adolescent girls has been undermined over time and their life chances have been affected, thereby making them most vulnerable to prostitution and use of drugs as a means of livelihood. The book concludes on socio-economic constraints as the primary factors that push adolescent girls into prostitution,drug use and all kinds of criminal behaviour in their various socio-cultural milieus. Because governments of various societies have overlooked the needs of the adolescent girls , ignoring the fact that they are the developmental pillar of tomorrow, this book recommends an urgent need to design and implement effective research studies, policies, prevention and intervention programmes to deal with the intricacies associated with prostitution, drug use and criminality among adolescent girls across a wide range of global societies.