Osamu Suzuki / Kanako Watanabe (eds.)

Drugs and Poisons in Humans

A Handbook of Practical Analysis
Herausgegeben:Suzuki, Osamu; Watanabe, Kanako

• Gebundenes Buch

Produktbeschreibung

This book has been arranged such that any analytical chemist can start analytical experiments for a drug or poison in a crude biological matrix, even if she/he has no experience of analyzing that compound. This is particularly useful in view of the acute risk of terrorist attacks in the world today.

The specimens to be analyzed are presumed to be complicated matrices (not clean waste or ground water) such as whole blood, tissues or urine, which contain cells, membranes, proteins and lipids in every chapter. Therefore, procedures for extraction of a drug or poison have been given in great detail.

Each chapter is composed of a rigid internal structure comprising Introduction, Reagents and their Preparation, Conditions of Analytical Instruments, Procedures, Assessment of the Methods, Poisoning Case Examples, Toxic and Lethal Concentrations in Human Specimens, Notes and References.

The chapters have been written by 67 authors who are experts engaged in analysis of each compound.

This type of book for analysis of drugs and poisons has not been published elsewhere in the world.

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Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists

Includes source of chemicals needed for the experiments

Texts are composed by 67 experts in analyzing the respective compounds

Clear and uniform structure of chapters for ease of reading

The text is illustrated by many diagrams and tables

Produktdetails

• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 10959534, 978-3-540-22277-4
• 2005
• Seitenzahl: 696
• Erscheinungstermin: 2. Mai 2005
• Englisch
• Abmessung: 241mm x 160mm x 47mm
• Gewicht: 1096g
• ISBN-13: 9783540222774
• ISBN-10: 3540222774
• Artikelnr.: 13127746

Autorenporträt

Osamu Suzuki, Hamamatsu City, Japan / Kanako Watanabe, Hamamatsu City, Japan

Inhaltsangabe

Chapters of general nature1) How to handle biological specimens2) Alternative specimens3) Pitfalls and cautions in analysis of drugs and poisons4) Pretreatments of human specimens5) Detection methods6) A computer system for diagnosis of causative drugs and poisons developed by the Japan Poison Information Center (Tokyo)7) Practical use of the poison-net developed by the Japan Poison Information Network (Hiroshima)8) Problems in toxin analysis in emergency medicine9) Analyses of chemical weapons and their related compounds Chapters on specific toxins 1. Volatile compounds1) Carbon monoxide2) Hydrogen sulfide and its metabolites3) Cyanide4) Methanol and formic acid5) Ethanol6) Chloroform and dichloromethane7) Toluene, benzene, xylene and stylene8) Alkyl nitrites9) Compenents of gasoline and kerosene 2. Controlled drugs1) Amphetamines and their metabolites2) Cannabinoids and their metabolites3) Morphine and its analogues4) Cocaine and its metabolites5) Pentazocine6) Lysergic acid diethylamide (LSD)7) 3,4-Methylenedioxyamphetamines8) Phencyclidine9) ?- Hydroxybutyric acid 3. Psychopharmaceuticals and hypnotics1) Phenothiazines2) Butyrophenones3) Tricyclic and tetracyclic antidepressants4) Benzodiazepines5) Bromisovalum6) Barbiturates 4. General drugs1) Diphenylmethane antihistaminics2) Propionic acid derivative analgesic-antipyretics3) Acetaminophen (paracetamol)4) Acetylsalicylic acid5) Antiepileptics6) Muscle relaxants7) ß- Blockers8) Local anaesthetics9) Salicylicacid10) ß- Lactam antibiotics 5. Chemicals of daily necessaries1) Hypochlorite2) Benzalkonium chlorides3) Hair dyes4) Permethrin5) Boric acid6) Naphthalene7) p-Dichlorobenzene8) Ethylene glycol 6. Natural toxins and alkaloids1) Aconite toxins2) Mushroom toxins3) Tetrodotoxin4) Methylxanthine derivatives5) Nicotine and cotinine6) Tropane alkaloids7) Oleander toxins 7. Pesticides1) Simultaneous analysis of pesticides by GC/MS2) Organophosphorus pesticides3) Glufosinate and glyphosate4) Carbamate pesticides5) Paraquat and diquat6) Cresol7) Diazine and triazine herbicides8) Coumarin rodenticides 8. Miscellaneous1) Sarin and its decomposition products2) VX and its decomposition products3) Sodium azide4) Arsenic compounds and other inorganic poisons5) Nitrate and nitrite compounds6) Methemoglobin